Single-Cell RNA-Sequencing Reveals the Active Involvement of Macrophage Polarizations in Pulmonary Hypertension

Figure 2

(a) Standard deviation (-axis) accounted for top 20 PCs (-axis) to identify the number of significant PCs based on the presence of an “elbow.” Approximately 15 PCS are chosen for the analysis. (b) Single cells onto 2-D UMAP space colored by assigned cell types. (c) Visualization of the data using t-distributed stochastic neighbor embedding (TSNE) after clustering based on transcriptomic similarity. (d) The proportion of cells in each cluster.

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