Single-Cell RNA-Sequencing Reveals the Active Involvement of Macrophage Polarizations in Pulmonary Hypertension

<div>(a) The sixteen classic markers known to distinguish M1-type macrophage from the other cells. (b) The top sixteen differential genes between the cluster 5 cells (M2-type macrophage) and cluster 13 cells (T cells expressing the CX3CR1 gene associated with M1-type macrophages). (c) The CX3CR1 was mainly expressed in cluster 13. (d) Volcano plot of differentially expressed genes between cluster 5 and cluster 13. Red and blue indicate higher expression and lower expression, respectively.</div>

Disease Markers

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Figure 3

Figure 3: Single-Cell RNA-Sequencing Reveals the Active Involvement of Macrophage Polarizations in Pulmonary Hypertension 