Single-Cell RNA-Sequencing Reveals the Active Involvement of Macrophage Polarizations in Pulmonary Hypertension

Table 1

The enriched GO and KEGG pathways of DEGs in the top three modules.

Cluster	Term	Description	Count	False discovery rate
Module 1
Go:BP	GO:0030100	Regulation of endocytosis	15	0.00060
Go:BP	GO:0060326	Cell chemotaxis	9
Go:CC	GO:0098772	Molecular function regulator	25	0.00060
Module 2
KEGG	mmu04144	Endocytosis	12	5.28e-06
Go:BP	GO:0043410	Positive regulation of MAPK cascade	5	8.45e-06
KEGG	mmu03320	PPAR signaling pathway	3	2.63e-05
KEGG	GO:0032088	Negative regulation of NF-kappaB transcription factor activity	3	2.63e-05
Module 3
Go:BP	GO:0001810	Regulation of type I hypersensitivity	3	1.10e-09
Go:BP	GO:0010818	T cell chemotaxis	3	0.0073
Go:BP	GO:0048247	Lymphocyte chemotaxis	9	1.58e-05
Go:BP	GO:0048247	Lymphocyte chemotaxis	9	<0.0001
Go:BP	GO:0030595	Leukocyte chemotaxis	12	<0.001
Go:BP	GO:0070098	Chemokine-mediated signaling pathway	6	8.80e-07
Go:MF	GO:0048020	CCR chemokine receptor binding	4	6.76e-05
KEGG	mmu04062	Chemokine signaling pathway	13	4.26e-13