Single-Cell RNA-Sequencing Reveals the Active Involvement of Macrophage Polarizations in Pulmonary Hypertension

Table 2

The hub genes identified by the MCODE plug-in.

Gene symbol	Description	Degree of connectivity	logFC
CX3CR1	The chemokine (C-X3-C) motif receptor 1	24	1.40
Ccl5	C-C motif chemokine5	22	1.13
C3ar1	C3a anaphylatoxin chemotactic receptor	42	1.29
Psap	Prosaposin	33	1.20
Gng11	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11	26	-1.9
Ccl9	C-C motif chemokine 9	20	3.42
Pf4	Platelet factor 4	27	2.48
Ccr2	C-C chemokine receptor type 2	25	1.90
Ccl6	C-C motif chemokine 6	22	3.62
Gpr183	G-protein coupled receptor 183	17	1.09
Cxcl16	C-X-C motif chemokine 16	22	1.15