Low EBI3 Expression Promotes the Malignant Degree of Gastric Cancer

Figure 1

EBI3 expression in gastric cancer (GC) cell lines and GC tissues. (a) The mRNA expression of EBI3 in GC cell lines MKN-45, MKN-28, MGC-803, HGC-27, and BGC-823 was detected, and the expression level of EBI3 was different in each GC cell line. The expression level was the lowest in MKN-45 and was significantly higher in BGC-823 and MGC-803 than other GC cell lines. (b) The mRNA and protein expression levels of EBI3 in gastric cancer tissues were significantly lower than those in paratumor tissues. (c) EBI3 expression was detected in tissue microarray by IHC. The expression levels of EBI3 in GC tissues were lower than that in paratumor tissues. The left column, ×40; the right column, ×200. , .

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