Low EBI3 Expression Promotes the Malignant Degree of Gastric Cancer

<div>EBI3 low expression promoted the viability, migration, invasion, and tumorigenicity abilities of BGC-823 cells. (a) The MTT assay showed that compared with the control group, the cell viability of the EBI3 overexpression group was significantly reduced, and the cell viability of the EBI3 interference group increased significantly. (b, c) After the cell scratched, the repair rate of the interference group was significantly faster than that of the control group, and the repair rate of the overexpression group was significantly slower than that of the control group. (d, e) The invasion experiments showed that compared with the control group, the invasive ability of BGC-823 cells in the overexpression group was inhibited, and the number of cell penetration was the least, while the invasive ability of BGC-823 cells in the interference group was significantly enhanced, and the number of cell penetration was the largest. <span class="nowrap"><svg height="10.7395pt" id="M70" style="vertical-align:-0.6370001pt" version="1.1" viewbox="-0.0498162 -10.1025 50.9184 10.7395" width="50.9184pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0091,0,0,-0.0091,0,-5.741)"><path d="M486 158C486 177 478 202 466 220C413 228 386 236 336 262C386 288 413 297 466 304C478 323 486 347 485 366C470 376 444 381 422 380C389 338 368 319 321 288C323 345 329 372 349 422C339 442 322 461 305 470C289 461 271 442 262 422C281 372 287 345 290 288C243 319 222 338 189 380C167 381 142 376 125 366C125 347 133 322 145 304C198 296 225 288 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Disease Markers

Low EBI3 Expression Promotes the Malignant Degree of Gastric Cancer

Figure 4