Expression and Clinical Significance of lncRNA NEAT1 in Patients with Spinal Tuberculosis
Table 2
The level of lncRNA NEAT1 in peripheral blood of STB patients.
Characteristic
lncRNA NEAT1_1
value
lncRNA NEAT1_2
value
High
Low
High
Low
Age (years)
0.687
0.969
<60
42 (35.0)
36 (30.0)
43 (35.8)
35 (29.2)
≧60
21 (17.5)
21 (17.5)
23 (19.2)
19 (15.8)
Sex
0.068
0.058
Male
37 (30.8)
26 (21.7)
34 (28.3)
29 (24.2)
Female
23 (19.2)
34 (28.3)
20 (16.7)
37 (30.8)
Locations of the lesions
0.751
0.825
Thoracic segment
29 (24.2)
25 (20.8)
24 (20.0)
30 (25.0)
Lumbar segment
30 (25.0)
30 (25.0)
28 (23.3)
32 (26.7)
Thoracic and lumbar segment
4 (3.3)
2 (1.7)
2 (1.7)
4 (3.3)
Segments of the lesions
≤0.001
≤0.001
2 segments
7 (5.8)
52 (43.3)
7 (5.8)
52 (43.3)
≧3 segments
56 (46.7)
5 (4.2)
47 (39.2)
14 (11.7)
Anti-TB treatment
≤0.001
≤0.001
2 weeks
51 (42.5)
9 (7.5)
43 (35.8)
17 (14.2)
>2weeks
12 (10.0)
48 (40.0)
11 (9.2)
49 (40.8)
Paraspinal abscesses
0.017
0.004
Yes
37 (30.8)
21 (17.5)
34 (28.3)
24 (20.0)
No
26 (21.7)
36 (30.0)
20 (16.7)
42 (35.0)
Drug resistance
≤0.001
≤0.001
Yes
4 (3.3)
28 (23.3)
4 (3.3)
28 (23.3)
No
59 (49.2)
29 (24.2)
50 (41.7)
38 (31.7)
Categorical variables are indicated as frequency and percentage. The calculated cut-off value for lncRNA NEAT1_1 and lncRNA NEAT1_2 was 3.82 and 2.30, respectively. Relative lncRNA NEAT1 levels below these cut-off values were described as “low,” and those above the value were described as “high.” values were determined using chi-square test and the Fisher exact test. value < 0.05 was considered statistically significant. TB: tuberculosis.
