Expression and Clinical Significance of lncRNA NEAT1 in Patients with Spinal Tuberculosis
Table 3
The level of lncRNA NEAT1 in granulomatous tissues of STB patients.
Characteristic
lncRNA NEAT1_1
value
lncRNA NEAT1_2
value
High
Low
High
Low
Age (years)
0.444
0.619
<60
41 (34.2)
37 (30.8)
39 (32.5)
39 (32.5)
≧60
19 (15.8)
23 (19.2)
23 (19.2)
19 (15.8)
Sex
0.107
0.104
Male
38 (31.7)
25 (20.8)
37 (30.8)
26 (21.7)
Female
26 (21.7)
31 (25.8)
25 (20.8)
32 (26.7)
Locations of the lesions
0.201
0.653
Thoracic segment
30 (25.0)
24 (20.0)
29 (24.2)
25 (20.8)
Lumbar segment
28 (23.3)
32 (26.7)
29 (24.2)
31 (25.8)
Thoracic and lumbar segment
5 (4.2)
1 (0.8)
4 (3.3)
2 (1.7)
Segments of the lesions
≤0.001
≤0.001
2 segments
6 (5.0)
53 (44.2)
3 (2.5)
56 (46.7)
≧3 segments
54 (45.0)
7 (5.8)
59 (49.2)
2 (1.7)
Anti-TB treatment
≤0.001
≤0.001
2 weeks
54 (45.0)
6 (5.0)
53 (44.2)
7 (5.8)
>2weeks
12 (10.0)
48 (40.0)
9 (7.5)
51 (42.5)
Paraspinal abscesses
0.002
0.003
Yes
39 (32.5)
19 (15.8)
38 (31.7)
20 (16.7)
No
26 (20.0)
36 (31.7)
24 (20.0)
38 (31.7)
Drug resistance
≤0.001
≤0.001
Yes
3 (2.5)
29 (24.2)
1 (0.8)
31 (25.8)
No
57 (47.5)
31 (25.8)
61 (50.8)
27 (22.5)
Categorical variables are indicated as frequency and percentage. The calculated cut-off value for lncRNA NEAT1_1 and lncRNA NEAT1_2 was 9.42 and 4.57, respectively. Relative lncRNA NEAT1 levels below these cut-off values were described as “low,” and those above the value were described as “high.” values were determined using chi-square test and the Fisher exact test. value < 0.05 was considered statistically significant. TB: tuberculosis.
