KLF4 Affects Acute Renal Allograft Injury via Binding to MicroRNA-155-5p Promoter to Regulate ERRFI1

Figure 6

Knocking down ERRFI1 antagonizes the effects of downregulated miR-155-5p on acute renal allograft injury. (a and b) RT-qPCR and Western blot detected ERRFI1 expression in renal tissues of mice. (c) Serum creatinine and eGFR contents in mice. (d) ELISA detected serum IFN-γ, TNF-α, and IL-2 contents in mice. (e) H&E staining detected kidney injury of mice. (f) TUNEL staining detected renal tubular apoptosis of mice. (g) Western blot detected Bax and Bcl-2 protein expressions in renal tissues of mice. (h) MDA content and SOD activity in renal tissues of mice. The data were expressed as ; compared with the miR-155-5p antagomir group, .

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