Research Article
KLF4 Affects Acute Renal Allograft Injury via Binding to MicroRNA-155-5p Promoter to Regulate ERRFI1
Figure 7
Knocking down ERRFI1 offsets the effects of downregulated miR-155-5p on H/R-treated HK-2 cell proliferation and apoptosis. (a and b) RT-qPCR and Western blot detected ERRFI1 expression in H/R-treated HK-2 cells. (c) CCK-8 assay detected the proliferation of H/R-treated HK-2 cells. (d) Flow cytometry detected the apoptosis rate of H/R-treated HK-2 cells. (e) Western blot detected Bax and Bcl-2 protein expression in H/R-treated HK-2 cells. The data were expressed as ; compared with the miR-155-5p inhibitor group, .
(a) |
(b) |
(c) |
(d) |
(e) |