Neutrophil-to-Lymphocyte Ratio, Platelet-to-Lymphocyte Ratio, and Their Variations as a Basis for a Prediction Model in Advanced NSCLC Patients Receiving Anlotinib
Table 3
Associations of NLR, PLR, and their variations with treatment response.
Treatment response
Pre-NLR
Pre-PLR
Post-NLR variation
Post-PLR variation
≤ 3.41
> 3.41
value
≤ 205.63
>205.63
value
Decrease
Rise
value
Decrease
Rise
value
PR
7 (4.6%)
3 (2.0%)
0.019
7 (4.6%)
3 (2.0%)
0.016
6 (3.9%)
4 (2.6%)
0.037
5 (3.3%)
5 (3.3%)
0.642
SD
56 (36.8%)
42 (27.6%)
62 (40.8%)
36 (23.7%)
58 (38.2%)
40 (26.3%)
61 (40.1%)
37 (24.3%)
PD
15 (9.9%)
29 (19.1%)
17 (11.2%)
27 (17.8%)
16 (10.5%)
28 (18.4%)
29 (19.1%)
15 (9.9%)
ORR
4.6%
2.0%
0.329
4.6%
2.0%
0.515
3.9%
2.6%
0.749
3.3%
3.3%
0.398
DCR
41.4%
29.6%
0.007
45.4%
25.7%
0.004
42.1%
28.9%
0.010
43.4%
27.6%
0.579
analyzed with chi-square test. analyzed with Fisher.