Research Article
TMUB1 Correlated with Immune Infiltration Is a Prognostic Marker for Colorectal Cancer
Table 2
Association between the expression of TMUB1 and clinicopathological features.
| | Characters | Level | Low expression of TMUB1 | High expression of TMUB1 | | Test |
| | | 310 | 309 | | | | T stage (%) | T1 | 5 (1.6%) | 15 (4.9%) | 0.046 | | | T2 | 46 (14.9%) | 59 (19.1%) | | | T3 | 218 (70.8%) | 204 (66.0%) | | | T4 | 39 (12.7%) | 31 (10.0%) | | | N stage (%) | N0 | 172 (56.0%) | 179 (57.9%) | 0.888 | | | N1 | 76 (24.8%) | 74 (23.9%) | | | N2 | 59 (19.2%) | 56 (18.1%) | | | M stage (%) | M0 | 226 (86.3%) | 233 (82.0%) | 0.219 | | | M1 | 36 (13.7%) | 51 (18.0%) | | | Pathologic stage (%) | Stage I | 43 (14.5%) | 62 (20.5%) | 0.065 | Exact | | Stage II | 121 (40.9%) | 106 (35.0%) | | Stage III | 95 (32.1%) | 84 (27.7%) | | Stage IV | 37 (12.5%) | 51 (16.8%) | | Gender (%) | Female | 148 (47.7%) | 141 (45.6%) | 0.656 | | | Male | 162 (52.3%) | 168 (54.4%) | | | CEA level (%) | <=5 | 124 (61.7%) | 128 (65.3%) | 0.52 | | | >5 | 77 (38.3%) | 68 (34.7%) | | | History of colon polyps (%) | NO | 182 (69.7%) | 182 (67.2%) | 0.586 | | | YES | 79 (30.3%) | 89 (32.8%) | | | Colon polyps present (%) | NO | 135 (70.7%) | 72 (67.3%) | 0.632 | | | YES | 56 (29.3%) | 35 (32.7%) | | | Neoplasm type (%) | Colon adenocarcinoma | 225 (72.6%) | 229 (74.1%) | 0.734 | | | Rectum adenocarcinoma | 85 (27.4%) | 80 (25.9%) | | | TP53 status (%) | Mut | 154 (55.8%) | 158 (63.2%) | 0.102 | | | WT | 122 (44.2%) | 92 (36.8%) | | | KRAS status (%) | Mut | 114 (41.3%) | 100 (40.0%) | 0.83 | | | WT | 162 (58.7%) | 150 (60.0%) | | | PIK3CA status (%) | Mut | 72 (26.1%) | 61 (24.4%) | 0.731 | | | WT | 204 (73.9%) | 189 (75.6%) | | | Residual tumor (%) | R0 | 218 (94.8%) | 232 (88.5%) | 0.001 | | | R1 | 5 (2.2%) | 1 (0.4%) | | | R2 | 7 (3.0%) | 29 (11.1%) | | | Race (%) | Asian | 8 (3.4%) | 4 (3.0%) | 0.21 | | | Black or African American | 35 (15.0%) | 30 (22.2%) | | | White | 191 (81.6%) | 101 (74.8%) | | | Age (%) | <=65 | 144 (46.5%) | 125 (40.5%) | 0.154 | | | >65 | 166 (53.5%) | 184 (59.5%) | | | Weight (%) | <=90 | 147 (72.8%) | 84 (69.4%) | 0.604 | | | >90 | 55 (27.2%) | 37 (30.6%) | | | Height (%) | <170 | 92 (46.9%) | 54 (50.0%) | 0.696 | | | > =170 | 104 (53.1%) | 54 (50.0%) | | | Age (median [IQR]) | | 67.00 [57.00, 75.00] | 68.00 [59.00, 77.00] | 0.165 | Nonnorm | | Height (median [IQR]) | | 170.00 [162.00, 177.00] | 169.00 [162.00, 175.25] | 0.577 | Nonnorm | | Weight (median [IQR]) | | 80.00 [65.43, 91.00] | 78.90 [64.50, 94.00] | 0.876 | Nonnorm |
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