Review Article

Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio in Poststroke Depression: A Systematic Review and Meta-Analysis

Table 1

Characteristics of studies included in the meta-analysis.

First authorStudy yearCountryAge group (years)LanguageStroke typeFollow-up period (month)Depression assessment toolSample sizeNLRPLRNOS score
PSDNPSDPSDNPSDPSDNPSD

Chen et al.2016China18-80EnglishND1HAMD782217
Stern et al.2017USA≥18EnglishICH/IVH12HDRS13767
Wang et al.2017China18-80EnglishND1HAMD451078
Quiqian et al.2019ChinaNDEnglishAIS1HAMD772868
Gong et al.2020China≥18EnglishICH3HAMD1072658
Hu et al.2020ChinaNDEnglishAIS6HAMD1042728
Xia et al.2020China42-80ChineseAIS3HAMD40708
Hu et al.2021China18-80EnglishAIS1HAMD1293036

PSD: poststroke depression; NPSD: nonpoststroke depression; NLR: neutrophil to lymphocyte ratio; PLR: platelet to lymphocyte ratio; ND: not declared; HAMD: Hamilton Depression Scale; HDRS: Hamilton Depression Rating Scale; HADS: the hospital anxiety and depression scale; AIS: acute ischemic stroke; ICH: hemorrhagic stroke; IVH: intraventricular hemorrhage; NOS: Newcastle-Ottawa scale.