Research Article

Relationship of Admission Serum Anion Gap and Prognosis of Critically Ill Patients: A Large Multicenter Cohort Study

Table 3

The mortalities in patients with different acid-base disorders.

TotalAG< 8 mmol/L8 ≤ AG ≤ 16 mmol/LAG> 16 mmol/L

Normal
 Subjects, (%)11671 (0.1)590 (50.6)576 (49.4)
 ICU mortality, (%)114 (9.8)1 (100.0)34 (5.8)79 (13.7)<0.001
 Hospital mortality, (%)187 (16.0)1 (100.0)60 (10.2)126 (21.9)<0.001
Acid-base disorder with a normal blood pH#
 Subjects, (%)243211 (0.5)1007 (41.4)1414 (58.1)
 ICU mortality, (%)276 (11.3)0 (0)77 (7.6)199 (14.1)<0.001
 Hospital mortality, (%)468 (19.2)1 (9.1)133 (13.2)334 (23.6)<0.001
Blood
 Subjects, (%)378527 (0.7)1186 (31.3)2572 (68.0)
 ICU mortality, (%)698 (18.4)6 (22.2)115 (9.7)577 (22.4)<0.001
 Hospital mortality, (%)952 (25.2)6 (22.2)155 (13.1)791 (30.8)<0.001
Blood pH>7.45
 Subjects, (%)11363 (0.3)455 (40.1)678 (59.7)
 ICU mortality, (%)134 (11.8)0 (0)35 (7.7)99 (14.6)0.001
 Hospital mortality, (%)202 (17.8)0 (0)58 (12.7)144 (21.2)0.001

Patients with , , and ; # patients with and abnormal HCO3- or PaCO2; values indicated the differences of mortalities between groups with serum and . AG, anion gap; ICU, intensive care unit.