Research Article

Polyphenol Extracts from Grape Seeds and Apple Can Reactivate Latent HIV-1 Transcription through Promoting P-TEFb Release from 7SK snRNP

Figure 4

Polyphenol extracts from grape seeds and apple promote the release of P-TEFb from 7SK snRNP. HeLa-based cells that were either untreated (−) or treated (+) with polyphenol extracts from grape seeds and apple (200 μM) were analyzed by western blotting for the indicated proteins. Anti-Flag immunoprecipitates (IP) derived from NE were tested by western blotting for the presence of the indicated proteins.