[Retracted] circCNN2 Accelerates Cell Proliferation and Invasion in Lung Squamous Cell Carcinoma via Regulating miR-184/E2F1 and Activating MAPK Signaling Pathway

Figure 2

circCNN2 promotes cell proliferation and invasion in LUSC. (a, b) CCK-8 and colony formation assays were conducted to evaluate the proliferative ability of H1703 and H226 cells after circCNN2 was silenced. (c) Western blot analysis was performed to examine the protein levels of PCNA and cyclin D1 in H1703 and H226 cells upon circCNN2 silencing. (d, e) Transwell assays were performed to analyze the effect of circCNN2 silencing on LUSC cell invasion. (f) Western blot analysis was used to examine the protein levels of invasion-related proteins MMP2 and MMP9 in LUSC cells. compared to the sh-NC group.

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