Research Article
Genomic Mutation Landscape of Primary Breast Lymphoma: Next-Generation Sequencing Analysis
Table 1
Baseline clinical characteristics of the total 40 primary breast lymphoma (PBL) patients.
| | Characteristics | | Percentage (%) |
| | Gender | | | | Female | 38 | 95 | | Male | 2 | 5 | | Age | | | | 60 | 13 | 32.5 | | <60 | 27 | 67.5 | | Ann Arbor stage | | | | I–II | 19 | 47.5 | | III–IV | 21 | 52.5 | | Ki-67 | | | | 70 | 28 | 70 | | <70 | 12 | 30 | | Bone marrow infiltration | | | | Absent | 32 | 80 | | Present | 8 | 20 | | B symptom | | | | Absent | 32 | 80 | | Present | 8 | 20 | | IPI | | | | 0–2 | 33 | 82.5 | | 3–5 | 7 | 17.5 | | LDH | | | | Normal | 24 | 60 | | Increase (>250) | 16 | 40 | | 2-MG | | | | Normal | 33 | 82.5 | | Increase (>250) | 7 | 17.5 | | Treatment | | | | RT + CT | 8 | 20 | | RT | 1 | 2.5 | | CT | 26 | 65 | | No treatment | 5 | 12.5 | | Pathologic types | | | | DLBCL | 32 | 80 | | MALT | 3 | 7.5 | | NK/T | 1 | 2.5 | | T cell | 1 | 2.5 | | B-LBL | 1 | 2.5 | | PBL | 1 | 2.5 | | Original site | | | | Left breast | 19 | 47.5 | | Right breast | 20 | 50 | | Bilateral breast | 1 | 2.5 |
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