Genomic Mutation Landscape of Primary Breast Lymphoma: Next-Generation Sequencing Analysis

Table 2

Clinical characteristics of 16 patients among the total 40 PBL patients undergoing next-generation sequence (NGS) analysis.

No.	Gender	Age	IPI	LDH	Surgical approach	Primary size	Treatment	Extranodal metastasis	Response vital	Status
#1	F	49	1	Normal	MRM		C + R	BM	SD	Dead
#2	F	59	2	Normal	TBR		None	No	NA	Alive
#3	F	46	0	Normal	PBR		C + R + ASCT	No	CR	Alive
#4	F	59	0	Normal	MRM		C + IT	No	CR	Alive
#5	F	46	0	Normal	TR		C + R	Bone	Cru	Alive
#6	F	67	1	Normal	MRM		C + IT	No	CR	Alive
#7	F	54	0	Normal	PBR		R	No	CR	Alive
#8	F	65	2	Elevated	PBR		C	Breast & face	PR	Alive
#9	F	71	1	Normal	TR		C	No	CR	Alive
#10	F	64	4	Elevated	TR		C + IT	Bone, breast, kidney	Cru	Alive
#11	F	71	4	Normal	PBR		C	Bone	NA	Dead
#12	F	60	2	Normal	TB		C	BM	Cru	Alive
#13	F	51	2	Elevated	TBR		C	No	PR	Dead
#14	F	71	4	Elevated	TB		C	No	CR	Dead
#15	F	28	0	Normal	TBR		C + R + ASCT+CART	No	CR	Dead
#16	F	40	0	Normal	TR		C	No	Cru	Dead

MRM: modified radical mastectomy; TBR: total breast resection; PBR: partial breast resection; TR: tumor resection; TB: tumor biopsy; C: chemotherapy; R: radiotherapy; ASCT: autologous stem cell transplantation; CART: chimeric antigen receptor T cell therapy.