Research Article

Decreased Preoperative Serum AGR as a Diagnostic Marker of Poor Prognosis after Radical Surgery of Upper Urinary Tract and Bladder Cancers from a Pooled Analysis of 9,002 Patients

Table 1

Population, Intervention, Comparator, Outcomes, and Study Designs (PICOS) structure.

ItemsPopulationsInterventionComparatorOutcomesStudy designs

Inclusion criteriaPatients diagnosed with urinary tract cancers including upper urinary tract urothelial carcinoma and bladder urothelial cancer had AGR pretreatment of radical surgery.AGR pretreatment (low)AGR pretreatment (high)Overall survival, cancer-specific survival, recurrence-free survival, progression-free survival, and metastasis-free survival.Clinical research.
Exclusion criteriaPatients with urinary tract cancers undergoing nonradical surgery or palliative therapy or no AGR pretreatment.OtherOtherPatient feelings; inadequate indicators.Letters, comments, reviews, case reports, abstracts, and animal experiment.

AGR: albumin-to-globulin ratio.