miR-373-3p Regulates the Proliferative and Migratory Properties of Human HTR8 Cells via SLC38A1 Modulation

Figure 2

HIF-1α overexpression abolished miR-373-3p inhibitor function in HTR8 cells. (a, b) qRT-PCR and western blot of the relative HIF-1α mRNA and protein levels in HTR8 after transfecting with oeNC and oeHIF-1α. vs oeNC. (c) qRT-PCR of SCL38A1 protein levels in HTR8 cells treated with miR-373-3p miNC or inhibitor after transfecting with oeHIF-1α. vs oeNC, vs oeNC, vs oeNC. vs miNC + oeHIF-1α. (d) Western blot of the SCL38A1 protein levels in HTR8 cells treated with miR-373-3p miNC or inhibitor after transfecting with oeHIF-1α. (e, f) The miR-373-3p inhibitor significantly promoted the proliferation and migration of HTR8 cells after transfecting with oeHIF-1α. vs oeNC, vs oeNC. vs miNC + oeHIF-1α.

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