A Four-miRNA-Based Diagnostic Signature for Rheumatoid Arthritis

Figure 1

The results of differentially expressed miRNAs. (a) The boxplot of expression of miRNAs after standardization in the GSE124373 dataset. Horizontal axis: sample; vertical axis: relative expression of miRNAs. (b) The PCA results of miRNAs in the GSE124373 dataset. Red: rheumatoid arthritis (RA); black: healthy subjects. The closer the distance, the more similar the miRNAs. (c) The volcano plot of differentially expressed miRNAs between RA samples vs. healthy samples. Horizontal axis: log2FC; vertical axis: -log10(FDR). Red: downregulated miRNAs; blue: upregulated miRNAs; green: nonsignificance. (d) The heat map of differentially expressed miRNAs between RA samples vs. healthy samples. Horizontal axis: differentially expressed miRNAs; vertical axis: samples. Red: high expression; blue: low expression.

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