Research Article

Linc00312 Single Nucleotide Polymorphism as Biomarker for Chemoradiotherapy Induced Hematotoxicity in Nasopharyngeal Carcinoma Patients

Table 5

Prediction of the risk of thrombocytopenia in NPC patients based on the interaction between rs12497104 and age.

Clinical factorsGenotypesThrombocytopeniaOR (95% CI)
Grade 0
(%)

(%)

Agers12497104 ()
 ≥47GG70 (68.0)33 (32.0)1.00 (reference)
 ≥47GA95 (79.2)25 (20.8)0.520 (0.278-0.971)0.040
 ≥47AA28 (84.8)5 (15.2)0.344 (0.114-1.038)0.058
 <47GG62 (87.3)9 (12.7)0.276 (0.120-0.635)0.002
 <47GA91 (84.3)17 (15.7)0.381 (0.192-0.755)0.006
 <47AA17 (94.4)1 (5.6)0.105 (0.013-0.883)0.038