Identification of the Metabolomics Signature of Human Follicular Fluid from PCOS Women with Insulin Resistance

Figure 1

PCOS-IR patients and PCOS-NIR patients exhibited distinct metabolic characteristics. Principal component analysis (PCA) score plots were drawn according to the metabolic profiling information obtained from follicular fluid (FF) of PCOS-IR and PCOS-NIR patients (; (a)). (b) Orthogonal projections to latent structures–discriminant analysis (OPLS-DA) score plots were drawn according to the metabolic profiling information obtained from the FF of PCOS-IR and PCOS-NIR patients (, , and ). The purple dots indicate PCOS-IR patients (IR), and the yellow dots indicate PCOS-NIR patients (NIR). (c) The OPLS-DA model was constructed by the permutation test ( and ). The green dots indicate , and the blue dots indicate .

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