Meta-Analysis of Efficacy and Safety of Karelizumab Combined with Apatinib in the Treatment of Advanced Gastric Cancer

Table 3

Meta-analysis of cytokine levels in blank group and observation group after treatment.

Cytokines	Number of studies	Sample size ()	OR	95% CI
IFN-γ	3	175	3.22	[1.91, 4.53]	<0.00001
TNF-α	3	175	1.60	[1.45, 1.75]	<0.00001
IL-10	2	127	-2.79	[-4.06, -1.52]	<0.001
IL-4	2	78	-2.08	[-2.71, -1.45]	<0.00001
TSGF	2	157	-12.27	[-21.67, -2.86]	0.01
CA199	4	227	-3.89	[-4.60, -3. 19]	<0.00001
CEA	4	227	-0.06	[-0.82, -0.51]	<0.00001