Research Article

SEC61G Promotes Cervical Cancer Proliferation by Activating MAPK Signaling Pathway

Figure 6

Gefitinib inhibits CC proliferation and tumor growth through SEC61G. (a) After SiHa cells were given gefitinib (10 μM, 24 h) or DMSO, the expression of SEC61G was analyzed by qRT-PCR. (b) EdU proliferation assay. (c) Transwell detection of invasive ability of CC cells. After 48 h, crystal violet staining was performed and counted. (d) Detection of E-cadherin expression e. (e) Vimentin expression detection. (f) Schematic description of the regulatory mechanism of CC proliferation through SEC61G/MAPK signaling and therapeutic targets. and vs. DMSO group.
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