Inferior ST-Segment Elevation Can Predict In-Hospital Mortality in Patients with Anterior Myocardial Infarction Complicated by Ventricular Septal Rupture

Table 1

Comparison of baseline clinical profiles between the two groups.

	Death group ()	Survival group ()	value
Age (years)	72 (63~78)	70 (62~75)	0.428
Male, (%)	32 (49.2%)	13 (65.0%)	0.213
Hypertension, (%)	34 (52.3%)	10 (50.0%)	0.894
Diabetes mellitus, (%)	11 (16.9%)	8 (40.0%)	0.061
Time from symptom onset to admission, (%)			<0.001
≤12 h	19 (29.3%)	4 (20.0%)
12 h~48 h	20 (31.0%)	1 (5.0%)
3 d~7 d	20 (31.0%)	3 (15.0%)
>7 d	6 (8.6%)	12 (60.0%)
Killip class IV, (%)	32 (49.2%)	3 (15.0%)	0.007
NT-proBNP (pg/mL)	8280 (3711~19509)	4016 (2282~8189)	0.074
ALT (U/L)	74 (50-351)	32 (19-65)	0.001
CRE (μmol/L)	101 (72-151)	83 (71-110)	0.171
Electrocardiography
Inferior STE, (%)	32 (49.2%)	3 (15.0%)	0.005
New-onset RBBB, (%)	22 (33.8%)	3 (15.0%)	0.103
Coexistence of inferior STE and RBBB, (%)	7 (10.8%)	1 (5.0%)	0.672
Echocardiography
LVEF (%)	45 (39~51)	46 (40~49)	0.634
Left ventricular aneurysm, (%)	30 (46.2%)	11 (55.0%)	0.489
Pericardial effusion, (%)	7 (35.0%)	17 (26.2%)	0.442
Apical VSR, (%)	19 (95.0%)	59 (90.8%)	1
VSR size (mm)	10.0 (7.0~12.8)	8.0 (6.0~12.8)	0.369
CAG ()			0.910
Single-vessel, (%)	7 (36.8%)	5 (31.3%)
Double-vessel, (%)	5 (26.3%)	4 (25.0%)
Multivessel, (%)	7 (36.8%)	7 (43.8%)
Primary PCI, (%)	14 (21.5%)	10 (50.0%)	0.017
CABG, (%)	2 (3.1%)	1 (5.0%)	0.558
Transcatheter closure/surgical repair for VSR,	1/4	5/7	<0.001
Time from symptom onset to VSR repair (d)	36 (19-44)	30 (24-33)	0.115

NT-proBNP: N-terminal probrain natriuretic peptide; ALT: serum alanine transaminase; CRE: creatinine; STE: ST-segment elevation; RBBB: right bundle branch block; LVEF: left ventricular ejection fraction; VSR: ventricular septal rupture; CAG: coronary angiography; PCI: percutaneous coronary intervention; CABG: coronary artery bypass grafting.