Serum and Cerebrospinal Fluid Testing in Optic Neuropathy Patients with Malignant Tumors

Figure 5

Ophthalmic and MRI examination of infiltrative optic neuropathy (right eye) and meningeal carcinomatosis-associated optic neuropathy (left eye) with leukemia in Case 13. Fundus photographs showed moderate swollen optic disc and posterior retinal edema with macular cherry red in the right eye (A), and mild swollen optic disc in the left eye (B). Visual field test was normal in the left eye (C). MRI showed enlarged optic nerve (short arrow, D, E, F) with sheath enhancement (long arrow, G) in the right eye, enlarged optic nerve sheath space (arrowhead, E, F) with sheath enhancement (long arrow, G) in the left eye. Focal linear enhancement of the meninge, and spotty and linear lesions with enhancement in basal ganglia (star, H) which supporting meningeal carcinomatosis found in T1-weighted MRI with contrast enhancement.

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