Research Article
[Retracted] PM2.5 Exposure Induces Lung Injury and Fibrosis by Regulating Ferroptosis via TGF-β Signaling
Figure 6
NAC reverses PM2.5-regulated ferroptosis in primary mouse lung epithelial cells. (a–i) The primary mouse lung epithelial cells were treated with PM2.5 or cotreated with NAC. (a) The ROS levels of were analyzed by flow cytometry analysis. (b, c) The expression of TGF-β, Smad3, and TET2 was analyzed by Western blot analysis. (d) The levels of 5hmC were examined by ELISA assays. (e) The expression of GPX4 and SLC7A11 was measured by Western blot. (f–i) The levels of iron, Fe2+, MDA, and GSH were detected in the cells. .
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