Research Article

[Retracted] CBR3-AS1 Accelerates the Malignant Proliferation of Gestational Choriocarcinoma Cells by Stabilizing SETD4

Figure 1

CBR3-AS1 silencing suppresses the malignant progression of GC in vitro. (a) RT-qPCR analysis of CBR3-AS1 expression in GC cells (JEG-3, BeWo, and JAR) and normal HTR-8 cells. (b) The knockdown efficiency of CBR3-AS1 in JEG-3 and BeWo cells was certified by RT-qPCR. (c, d) GC cell proliferation was analyzed with CBR3-AS1 silencing through CCK-8 and colony formation assays. (e, f) Flow cytometry analysis on cell cycle and cell apoptosis was performed with CBR3-AS1 downregulation. (g) Western blot analysis on the level of cell cycle-related proteins (Cyclin D1, p21, and p16) and cell apoptosis-related proteins (Bcl-2 and Bax). ; .
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