Phenytoin Is Promoting the Differentiation of Dental Pulp Stem Cells into the Direction of Odontogenesis/Osteogenesis by Activating BMP4/Smad Pathway

Table 3

Docking results of the active components of phenytoin with odontogenic/osteogenic genes.

Protein	Ligand	Affinity (kcal/Mol)	Center_x	Center_y	Center_z	Size; x	Size; y	Size; z
BMP4	CID1775	-7.2	21.346	15.236	-7.845	19	19	19
COL11A1		-7.4	16.664	-1.218	-17.799	32	25	19
FGFR2		-8.7	25.333	-5.704	1.311	19	19	19
IGF2		-6.4	-1.713	19.078	11.731	19	19	19
MDK		-6.1	-0.753	-2.399	14.09	19	19	19
MMP2		-6.8	1.572	-4.634	6.759	19	19	19
PBX1		-8.7	-0.72	24.956	7.494	34	25	29
S1PR1		-7.4	1.77	13.365	-10.656	26	19	27
SCN5A		-6.6	-1.108	2.056	22.412	19	19	19
TGFB3		-6.7	-21.547	20.42	23.061	19	19	19
TIMP1		-8.2	146.459	-7.049	4.149	19	19	19