Research Article
Identification of Potential Key Biomarkers and Immune Infiltration in Oral Lichen Planus
Table 1
KEGG and Reactome pathway enrichment analyses for differentially expressed genes (
).
| | ID | Terms | Count | value |
| | Upregulated | | | | | hsa04512 | ECM-receptor interaction | 9 | 3.06-07 | | hsa04974 | Protein digestion and absorption | 8 | 4.79-06 | | hsa05146 | Amoebiasis | 7 | 1.65-04 | | hsa04510 | Focal adhesion | 9 | 1.80-04 | | hsa04611 | Platelet activation | 6 | 0.00336272 | | hsa04151 | PI3K-Akt signaling pathway | 9 | 0.005079306 | | hsa04145 | Phagosome | 6 | 0.006175871 | | hsa05144 | Malaria | 4 | 0.006529778 | | hsa04726 | Serotonergic synapse | 5 | 0.0109323 | | hsa00590 | Arachidonic acid metabolism | 4 | 0.011940849 | | hsa05323 | Rheumatoid arthritis | 4 | 0.031412058 | | hsa04912 | GnRH signaling pathway | 4 | 0.034212174 | | hsa04750 | Inflammatory mediator regulation of TRP channels | 4 | 0.041234535 | | hsa04940 | Type I diabetes mellitus | 3 | 0.042639686 | | hsa02010 | ABC transporters | 3 | 0.046388375 | | Downregulated | | | | | R-HSA-211859 | Biological oxidations | 11 | 1.950-7 | | R-HSA-5579029 | Metabolic disorders of biological oxidation enzymes | 3 | 1.380-4 | | hsa00982 | Drug metabolism-cytochrome P450 | 4 | 0.002280447 | | hsa00340 | Histidine metabolism | 3 | 0.003265313 | | hsa00260 | Glycine, serine, and threonine metabolism | 3 | 0.010053474 | | hsa00380 | Tryptophan metabolism | 3 | 0.010557146 | | hsa00330 | Arginine and proline metabolism | 3 | 0.016186014 | | hsa01100 | Metabolic pathways | 10 | 0.037458967 |
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