Research Article

Potential Effects of Metformin on the Vitality, Invasion, and Migration of Human Vascular Smooth Muscle Cells via Downregulating lncRNA-ATB

Figure 2

LncRNA-ATB triggers viability, migratory, and invasive abilities in VSMCs. (a) Transfection of pcDNA-lncRNA-ATB effectively upregulated lncRNA-ATB in VSMCs. (b) CCK-8 assay showed dose-dependently increased viability in VSMC overexpressing lncRNA-ATB. (c) Transwell assay showed enhanced migration in VSMC overexpressing lncRNA-ATB. (d) Transwell assay showed enhanced invasion in VSMC overexpressing lncRNA-ATB.
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