Research Article

Potential Effects of Metformin on the Vitality, Invasion, and Migration of Human Vascular Smooth Muscle Cells via Downregulating lncRNA-ATB

Figure 4

LncRNA-ATB inhibits p53 level. (a) RIP assay showed that lncRNA-ATB interacted with p53. (b) Serum level of p53 was lower in CHD patients than healthy subjects. (c) Pearson correlation analysis showed a negative correlation between serum levels of lncRNA-ATB and p53 in CHD patients. (d) Overexpression of lncRNA-ATB downregulated p53 in VSMCs.
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