Potential Effects of Metformin on the Vitality, Invasion, and Migration of Human Vascular Smooth Muscle Cells via Downregulating lncRNA-ATB

<div>Regulatory effects of lncRNA-ATB on VSMCs require the interaction with p53. (a) P53 was upregulated by metformin induction in VSMCs. (b) Overexpression of p53 abolished the role of lncRNA-ATB in promoting VSMC proliferation. (c) Overexpression of p53 abolished the role of lncRNA-ATB in promoting VSMCs migration. (d) Overexpression of p53 abolished the role of lncRNA-ATB in promoting VSMC invasion.</div>

Disease Markers

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Figure 5

Figure 5: Potential Effects of Metformin on the Vitality, Invasion, and Migration of Human Vascular Smooth Muscle Cells via Downregulating lncRNA-ATB 

Figure 5 | Potential Effects of Metformin on the Vitality, Invasion, and Migration of Human Vascular Smooth Muscle Cells via Downregulating lncRNA-ATB 