COPS3 Promotes Proliferation, Invasion, and EMT of Colorectal Cancer Cells by MEK/ERK Pathway

<div>COPS3 depletion suppressed tumor growth <i>in vivo</i>. (a) The representative images of tumors in control and COPS2 siRNA transfection mice and the tumor growth curve. (b) IHC assays showed the expression of COPS2 in tumors in control and COPS2 siRNA transfection mice. (c) Immunoblot showed the expression of COPS2, E-cadherin, Erk, p-Erk, Mek, and p-Mek in tumors from control and COPS2 siRNA transfection mice. 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d="M384 0V27C293 34 287 42 287 114V635C232 613 172 594 109 583V559L157 557C201 555 205 550 205 499V114C205 42 199 34 109 27V0H384Z"></path></g></svg>,</span> siCOPS3 vs. siControl.</div>

Disease Markers

fig6

Figure 6

Figure 6: COPS3 Promotes Proliferation, Invasion, and EMT of Colorectal Cancer Cells by MEK/ERK Pathway 