Research Article

Changes of Tumor Markers in Patients with Breast Cancer during Postoperative Adjuvant Chemotherapy

Table 5

Analysis of influencing factors of CEA change magnitude during chemotherapy.

FactorChange magnitude of CEAUnivariate analysisMultivariate analysis

Age
 ≤570.3530.554
 >57
Menstruation
 Yes1.2290.271
 No
Comorbidities
 No2.0610.155
 Yes
BMI
 ≤240.1360.713
 >24
Tumor size
 ≤2 cm
 >2 cm
Nodal status
 07.5600.00115.1170.000
 1-3
 ≥ 4
HR status
 Positive8.0790.00614.8340.000
 Negative
ALT change magnitude
 ≤0.130.47 ± 0.480.2940.589
 >0.130.42 ± 0.48
AST change magnitude
 ≤0.050.6320.429
 0.05
rGT change magnitude
 ≤0.358.9740.0048.5590.004
 >0.35
Triglyceride change magnitude
 ≤0.180.0430.835
 >0.18
Cholesterol change magnitude
 ≤0.0770.0650.799
 >0.077
Fasting blood glucose change magnitude
 ≤0.051.1130.294
 >0.05
Initial WBC
 ≤6.270.0450.833
 >6.27
Initial NEUT
 ≤3.500.8550.358
 >3.50
Initial MONO
 ≤0.290.2980.586
 >0.29
Initial LY
 ≤1.952.0100.160
 >1.95
Initial PLT/LY
 ≤117.540.2030.654
 >117.54
Initial NEUT/LY
 ≤1.744.9000.0297.0780.009
 >1.74
Initial LY/MONO
 ≤6.610.45 ± 0.480.0000.982
 >6.610.45 ± 0.49
Initial SII
 ≤410.691.0070.318
 >410.69