Disease Markers

Research Article

Serum Sclerostin and Its Association with Bone Turnover Marker in Metabolic Bone Diseases

Table 2

Basic characters of OI and the control group.


	Control ()	OI ()	P

Age (year)			—
Sex (male/female)	43/28	43/28	—
BMI (kg/m²)			0.146
β-CTX (ng/L)	435.00 (300.00, 640.00)	793.10 (433.05, 1140.00)	0.001
PTH (pg/mL)	39.90 (30.88, 60.70)	27.62 (20.27, 45.18)	0.003
25OHD (ng/mL)	18.43 ± 5.73	23.18 ± 12.52	0.057
Sclerostin (pmol/L)	38.00 (27.06, 68.52)	130.50 (96.12, 160.80)	< 0.001

BMI: body mass index; β-CTX: β-CrossLaps of type 1 collagen containing cross-linked C-telopeptide; PTH: parathyroid hormone; 25OHD: 25-hydroxyvitamin D; OI: osteogenesis imperfecta. Normally distributed data are presented as the (SD), nonnormally distributed data are presented as the median (interquartile range).