An Integrative Bioinformatic Analysis of Microbiome and Transcriptome for Predicting the Risk of Colon Adenocarcinoma

Figure 3

Profiling the gene expression of the high-risk microbiome-related genes. (a) A volcano plot of the DEGs between high- and low-risk groups of COAD samples. (b) Bar graphs showing the enriched KEGG pathways of the risk DEGs. GSEA plots showed the upregulated (c) PPAR signaling and the downregulated (d) IL17 signaling. (e) Bar graphs showing the CIBERSORT estimated infiltration of immune cell subsets into the COAD high- and low-risk samples.

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