An Integrative Bioinformatic Analysis of Microbiome and Transcriptome for Predicting the Risk of Colon Adenocarcinoma

Table 1

Top gut microbial correlating with high or lower risk of colon cancer mortality.

Gene	Coefficie nt	P value	Gene	Coefficient	P value
Piscirickettsiaceae	247.19	P < 0.001	Mesoaciditogaceae	-140.792	P < 0.001
Syntrophaceae	114.643	P < 0.001	Hyphomonadaceae	-107.232	P < 0.001
Listeriaceae	87.535	P < 0.001	Bacillaceae	-85.157	P < 0.001
Aquificaceae	86.796	P < 0.001	Thermoanaerobacterales_Family_IV._Incertae_Sedis	-72.364	P < 0.001
Comamonadaceae	79.195	P < 0.001	Peptococcaceae	-61.483	P < 0.001
Ignavibacteriaceae	62.405	P < 0.001	Alcanivoracaceae	-59.424	P < 0.001
Mariprofundaceae	54.515	P < 0.001	Actinomycetaceae	-56.622	P < 0.001
Chromobacteriaceae	41.484	P < 0.001	Syntrophorhabdaceae	-56.583	P < 0.001
Limnochordaceae	40.748	P < 0.001	Rickettsiaceae	-54.024	P < 0.001
Acidothermaceae	39.392	P < 0.001	Ruminococcaceae	-53.921	P < 0.001
Phyllobacteriaceae	36.895	P < 0.001	Rhodospirillaceae	-48.748	P < 0.001
Symbiobacteriaceae	35.305	P < 0.001	Alicyclobacillaceae	-43.438	P < 0.001
Bacteroidaceae	35.118	P < 0.001	Oscillochloridaceae	-41.465	P < 0.001
Salinisphaeraceae	35.031	P < 0.001	Gallionellaceae	-39.995	P < 0.001
Chitinivibrionaceae	34.137	P < 0.001	Methylothermaceae	-37.641	P < 0.001
Marinilabiliaceae	33.292	P < 0.001	Mycobacteriaceae	-36.452	P < 0.001
Frankiaceae	33.195	P < 0.001	Caldisericaceae	-36.349	P < 0.001
Marinifilaceae	32.807	P < 0.001	Sporichthyaceae	-35.514	P < 0.001
Oleiphilaceae	32.446	P < 0.001	Cryptosporangiaceae	-33.537	P < 0.001
Halobacteriovoraceae	31.806	P < 0.001	Burkholderiaceae	-33.496	P < 0.001
Puniceicoccaceae	30.899	P < 0.001	Fimbriimonadaceae	-32.953	P < 0.001
Magnetococcaceae	28.051	P < 0.001	Kordiimonadaceae	-31.766	P < 0.001
Nannocystaceae	26.418	P < 0.001	Saccharospirillaceae	-31.468	P < 0.001
Porticoccaceae	25.824	P < 0.001	Jiangellaceae	-29.333	P < 0.001
Nakamurellaceae	24.696	P < 0.001	Promicromonosporaceae	-28.741	P < 0.001
Eubacteriaceae	23.719	P < 0.001	Legionellaceae	-26.135	P < 0.001
Rubrobacteraceae	23.458	P < 0.001	Cellvibrionaceae	-21.792	P < 0.001
Ferrimonadaceae	22.347	P < 0.001	Gordoniaceae	-21.702	P < 0.001