Diagnosis of Genital Tuberculosis in Infertile Women by Using the Composite Reference Standard
Table 1
Performance of the Imaging methods for the diagnosis of FGTB: sensitivity, specificity, and kappa agreement in comparison with composite reference standards.
USG
CRS
HSG
CRS
12/62
TB group ()
Non-TB group (n =54)
16/43
TB group ()
Non-TB group ()
Positive ()
6
6
Positive ()
5
11
Negative ()
2
48
Negative ()
1
26
Sensitivity
80.00%, (95% CI: 44.39% to 97.48%)
Sensitivity
85.71% (95% CI: 42.13% to 99.64%)
Specificity
88.89%, (95% CI: 77.37% to 95.81%)
Specificity
70.27% (95% CI: 53.02% to 87.13%)
PPV
57.14%, (95% CI: 37.10% to 75.09%)
PPV
35.29%, (95% CI: 23.39% to 49.26%)
NPV
96.00%, (95% CI: 87.81% to 98.77%)
NPV
96.30%, (95% CI: 80.71% to 99.38%)
Kappa value (95% CI)
Agreement
Level of agreement
Kappa value (95% CI)
Agreement
Level of agreement
0.52 (0.24 to 0.81)
72.74%
Moderate
0.31 (0.053 to 0.57)
59.22%
Fair
PPV: positive predictive value; NPV: negative predictive value; TB group: TB-suspected patients; PCR: polymerase chain reaction; CRS: composite reference standard. For patients with suspicion of FGTB, diagnosis of TB was given if any two of culture/histopathology/radiological findings were positive.
