Diagnosis of Genital Tuberculosis in Infertile Women by Using the Composite Reference Standard

Table 4

Performance of the PCR and HPE for the diagnosis of FGTB: sensitivity, specificity, and kappa agreement in comparison with composite reference standards.

PCR	CRS		HPE	CRS
5/62	TB group ()	Non-TB group ()	4/62	TB group ()	Non-TB group ()
Positive ()	3	2	Positive ()	3	1
Negative ()	0	57	Negative ()	1	57
Sensitivity	100.00% (95% CI: 29.24% to 100.00%)		Sensitivity	75% (95% CI: 19.41% to 99.37%)
Specificity	96.61% (95% CI: 88.29% to 99.59%)		Specificity	98.28% (95% CI: 90.76% to 99.96%)
PPV	60.00% (95% CI: 27.75% to 85.42%)		PPV	75.00% (95% CI: 28.29% to 95.78%)
NPV	100.00%		NPV	99.28% (95% CI: 91.26% to 99.68%)
Kappa value (95% CI)	Agreement	Level of agreement	Kappa value (95% CI)	Agreement	Level of agreement
0.73 (0.38 to 1.0)	87.88%	Substantial	0.73 (0.37 to 1.0)	87.93%	Substantial