Hsa_circ_0097271 Knockdown Attenuates Osteosarcoma Progression via Regulating miR-640/MCAM Pathway

Figure 5

Circ_0097271 targeted miR-640 to promote OS cell malignant behaviors. Saos-2 and SW1353 cells were transfected with si-circ, si-NC, inhibitor, inhibitor-NC, or si-circ+inhibitor, and then used in the following experiments. (a) MiR-640 expression in these transfected cells was checked by qPCR. (b) The proliferation of these transfected cells was assessed by CCK-8 assay. (c) Clone formation capacity of these transfected cells was assessed by colony formation assay. (d) The migration of these transfected cells was assessed by Transwell assay. , relative to si-NC; ^#, ^## relative to inhibitor-NC; ^&, ^&& relative to si-circ+inhibitor.

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