Changes in Degree Centrality and Functional Connectivity after the First Cycle of Neoadjuvant Chemotherapy in Newly Diagnosed Breast Cancer: A Longitudinal Study

Table 2

Comparison of the neuropsychological test results between the NAC group at TP0 and the HC group.

Neuropsychological test	NAC TP0	HC group	value
	()	()
General cognition
FACT-Cog	113.05 (101.65, 118.60)	110.45 (94.95, 117.10)	0.28
PCI	60.30 (57.83, 64.80)	59.40 (51.30, 63.23)	0.12
Oth	16.00 (15.00, 16.00)	16.00 (14.00, 16.00)	0.42
PCA	21.00 (16.30, 21.80)	20.61 (16.13, 21.80)	0.96
QOL	16.00 (12.25, 16.00)	16.00 (15.00, 16.00)	0.28
Executive function and psychomotor speed
TMT-A	56.50 (34.25, 90.00)	42.00 (30.00, 57.75)	0.11
Mental flexibility
VFT	37.00 (31.00, 42.75)	32.50 (27.00, 39.25)	0.10
Working memory
DST forwards	7.00 (6.00, 8.00)	10.00 (8.75, 12.00)	<0.001
DST backwards	4.00 (4.00, 5.00)	4.00 (4.00, 6.00)	0.63
Anxiety and depression
SAS	27.50 (26.00, 32.00)	27.50 (25.00, 31.25)	0.79
SDS	26.00 (25.00, 30.00)	26.00 (25.00, 30.00)	0.94

Nonnormal distribution data are reported as . For the intergroup comparison, the value was obtained using the Mann–Whitney test. Abbreviations: FACT-Cog: Functional Assessment of Cancer Therapy-Cognitive Function; PCI: perceived cognitive impairments; Oth: comments from others; PCA: perceived cognitive abilities; QOL: impact on quality of life; TMT-A: Trail Making Test A; VFT: Verbal Fluency Test; DST: Digital Span Test; SAS: Self-Rating Anxiety Scale; SDS: Self-Rating Depression Scale.