The Neuronal Transcription Factor Creb3l1 Potential Upregulates Ntrk2 in the Hypertensive Microenvironment to Promote Vascular Smooth Muscle Cell-Neuron Interaction and Prevent Neurons from Ferroptosis: A Bioinformatic Research of scRNA-seq Data

<div>Definition and identification of key transcription factors. Analysis of neuron-specific transcription factor activity (a). Cluster map of identified key transcription factors with Foxp2, Twist2, Creb3l1, and Tcf21 located in the M2 module while Ets, Klf16, and Sp1 are located in the M5 module (b). Distribution of tSNE of identified core transcription factors (Ngf, Ntf3, Cxcr4, and Ntrk2) and their expression levels in each subpopulation of cells (c). Distribution of tSNE of key neuropeptide-related genes Ets1, Klf16, Sp1, and Creb3l1 and their expression in various subpopulations of cells (d).</div>

Disease Markers

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Figure 3: The Neuronal Transcription Factor Creb3l1 Potential Upregulates Ntrk2 in the Hypertensive Microenvironment to Promote Vascular Smooth Muscle Cell-Neuron Interaction and Prevent Neurons from Ferroptosis: A Bioinformatic Research of scRNA-seq Data 

Figure 3 | The Neuronal Transcription Factor Creb3l1 Potential Upregulates Ntrk2 in the Hypertensive Microenvironment to Promote Vascular Smooth Muscle Cell-Neuron Interaction and Prevent Neurons from Ferroptosis: A Bioinformatic Research of scRNA-seq Data 