Cancer-Associated Exosomal CBFB Facilitates the Aggressive Phenotype, Evasion of Oxidative Stress, and Preferential Predisposition to Bone Prometastatic Factor of Breast Cancer Progression

<div>Metastatic breast cancer cells secrete exosomes rich in CBFB and facilitate the transformation of cancer-associated fibroblast-like phenotype cells (CAF-like phenotype cells). CAF-like cells, and exosomal CBFB in turn promote epithelial-to-mesenchymal (EMT) transition of breast cancer cells, prompting increased bone metastasis incidence.</div>

Disease Markers

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Figure 6

Figure 6: Cancer-Associated Exosomal CBFB Facilitates the Aggressive Phenotype, Evasion of Oxidative Stress, and Preferential Predisposition to Bone Prometastatic Factor of Breast Cancer Progression 

Figure 6 | Cancer-Associated Exosomal CBFB Facilitates the Aggressive Phenotype, Evasion of Oxidative Stress, and Preferential Predisposition to Bone Prometastatic Factor of Breast Cancer Progression 