Tumor Suppressor Role and Clinical Significance of the FEV Gene in Prostate Cancer

Table 1

Correlation between FEV mRNA expression and various clinicopathological characteristics of PCa patients.

Clinical features	FEV with median subtraction in DASL dataset ()			FEV in TCGA dataset ()
	Cases			Cases
Age (years)
<66	127		0.248	354		0.082
≥66	64			142
Serum PSA levels (ng/mL)
<4	19		0.090	52		0.280
≥4	103			422
Gleason score
<7	69		<0.001	44		<0.001
=7	97			247
>7	25			205
Pathological stage
T2 < T3A	144	0.00 ± 0.74	0.015	177	8.02 ± 1.93	0.026
T3 ≥ T3A	47	-0.31 ± 0.79		128	7.60 ± 2.05
Surgical margin
Negative	114		0.358	312		<0.001
Positive	77			151
PSA failure
Negative	114		0.003	370		0.021
Positive	77			59
Metastasis
No	153		0.037	415		<0.001
Yes	24	-		82
OS
Alive	158		0.169	486		0.708
Died	19			10