Triptolide Inhibits the Biological Processes of HUVECs and HepG2 Cells via the Serine Palmitoyltransferase Long Chain Base Subunit 2/Sphingosine-1-Phosphate Signaling Pathway

Figure 1

TP inhibited the proliferation, migration, adhesion, and angiogenesis of HUVECs. (a) A CCK-8 assay was used to determine HUVECs proliferation after treatment with TP (0, 12.5, 25, or 50 nM), DMSO, and endostatin (8 mg/L) for 24, 48, and 72 h. After treating HUVECs with TP (0, 12.5, 25, or 50 nM), DMSO, and endostatin (8 mg/L) for 24 h, the migration (b), adhesion (c), and angiogenesis (d) of HUVECs were measured. , versus the control group.

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