Iodine-125 Seeds Inhibit Carcinogenesis of Hepatocellular Carcinoma Cells by Suppressing Epithelial-Mesenchymal Transition via TGF-<i>β</i>1/Smad Signaling

<div>I-125 seed radiation suppressed the growth of PLC cells xenografts in mice. (a) Growth curves presented the volumes of xenograft tumor treated with I-125 seed radiation. (b) Images of the harvested tumors. (c) Weight of harvested tumors was measured 28 days after treatment. H &amp; E staining (d) and immunohistochemistry (e). The positive expression of TGF-<i>β</i>1 in control and I-125 was quantitatively analyzed (f). 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Disease Markers

fig6

Figure 6

Figure 6: Iodine-125 Seeds Inhibit Carcinogenesis of Hepatocellular Carcinoma Cells by Suppressing Epithelial-Mesenchymal Transition via TGF-<i>β</i>1/Smad Signaling 

Figure 6 | Iodine-125 Seeds Inhibit Carcinogenesis of Hepatocellular Carcinoma Cells by Suppressing Epithelial-Mesenchymal Transition via TGF-β1/Smad Signaling 