Research Article
Prognostic Value of Arterial Lactate Metabolic Clearance Rate in Moderate and Severe Acute Pancreatitis
Table 1
Demographic, baseline characteristics, and outcomes of patients with moderate and severe acute pancreatitis.
| | Total () | Normal lactate () | Elevated lactate () | value |
| | Age | 46 (37-59) | 47 (37-60) | 46 (37-59) | 0.877 | | Male, N (%) | 259 (66.4) | 120 (67.0) | 139 (65.9) | 0.809 | | WBC, /L | 13.2 (9.9-17.8) | 13.0 (9-16.5) | 13.6 (10.2-18.5) | 0.030 | | Hematocrit | | | | <0.001 | | CRP, mg/L | 212.5 (143-325.0) | 204 (134-302) | 216 (150-347) | 0.068 | | Procalcitonin, ng/mL | 1.4 7(0.34-5.70) | 0.95 (0.31-2.42) | 2.34 (0.45-10.58) | <0.001 | | Cr, umol/L | 74 (56-113) | 62 (53-83) | 92 (60-155) | <0.001 | | BUN, mmol/L | 6.3 (4.2-9.7) | 5.1 (3.8-7.6) | 7.3 (5.0-10.8) | <0.001 | | APACHE II score | 10 (7-14) | 9 (6-12) | 11 (8-15) | 0.002 | | SIRS score | 2 (2-3) | 2 (2-3) | 2 (2-3) | <0.001 | | Mechanical assisted ventilation, N (%) | 138 (35.4) | 39 (21.8) | 99 (46.9) | <0.001 | | Sepsis, N (%) | 40 (10.3) | 9 (5.0) | 31 (14.7) | 0.002 | | ACS, N (%) | 35 (9) | 5 (2.8) | 30 (14.2) | <0.001 | | Persistent respiratory failure, N (%) | 254 (65.1) | 102 (57.0) | 152 (72.0) | 0.002 | | Persistent renal failure, N (%) | 73 (18.7) | 14 (7.8) | 59 (28.0) | <0.001 | | Continuous circulatory failure, N (%) | 10 (2.6) | 2 (1.1) | 8 (3.8) | 0.117 | | PMOF, N (%) | 68 (17.4) | 13 (7.3) | 55 (26.1) | <0.001 | | Infectious pancreatic necrosis, N (%) | 96 (24.6) | 30 (16.8) | 66 (31.3) | 0.001 | | In hospital mortality, N (%) | 68 (17.4) | 17 (9.5) | 51 (24.2) | <0.001 | | Length of hospital stay, day | 15 (10-26) | 12 (8-18) | 19 (11-33) | <0.001 | | ICU days, day | 7 (2-14) | 4 (0-9) | 9 (3-19) | <0.001 |
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WBC: white blood count; Cr: serum creatinine; BUN: blood urea nitrogen; CRP: C-reactive protein; ACS: abdominal compartment syndrome; PMOF: persistent multiple organ failure; ICU: intensive care unit; N: number.
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