Moxifloxacin Induced Liver Injury by Causing Lachnospiraceae Deficiency and Interfering with Butyric Acid Production through Gut–Liver Axis

Figure 1

The flow chart of the experimental research framework. Moxifloxacin (0, 36, 72, and 108 mg/kg body weight) was administered orally for 21 days. In each group, six rats were euthanized after anesthetization on days 3, 7, 14, and 21. Serum and colon contents were collected at each time point for metabonomics and 16S rRNA gene sequencing, respectively.